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苍夷通窍熏蒸液联合鼻渊通窍颗粒内服治疗变应性鼻炎的临床研究*
作者:栗世婷 赵丽辉 赵桂柱# 
单位:内蒙古包钢医院 内蒙古 包头 014010 
关键词:变应性鼻炎 鼻渊通窍颗粒 苍夷通窍熏蒸液 VAS评分 生活质量 
分类号:R 256.59
出版年,卷(期):页码:2026,43(1):1-4
摘要:

 摘要:目的 探讨苍夷通窍熏蒸液联合鼻渊通窍颗粒内服治疗变应性鼻炎(allergic rhinitis,AR)的临床疗效。方法 本研究选取2023年7月—2024年11月期间在内蒙古包钢医院耳鼻喉门诊确诊为AR的70例患者,依据就诊时间顺序将其分为对照组和实验组,每组各35例。对照组接受口服鼻渊通窍颗粒治疗,而实验组在此基础上增加了我院自制的苍夷熏蒸液进行口鼻部熏蒸治疗。对比治疗前后两组患者的症状严重程度(采用视觉模拟评分法VAS评估)、疗效评定、药物安全性评价以及鼻结膜炎生活质量调查问卷(RQLQ)评分。结果 治疗后,两组患者的鼻塞、鼻痒、喷嚏、流清水样鼻涕等症状均有显著改善,且实验组的症状缓解程度优于对照组,组间比较差异均有统计学意义(t=16.494、19.160、19.832、15.885,均P<0.05)。治疗后,实验组的疗效评价总有效率达到了82.86%,明显高于对照组的57.14%,组间比较差异有统计学意义(χ2=8.413,P<0.05)。治疗期间,两组药物不良反应发生率无统计学差异(χ2=0.000,P>0.05)。治疗后,两组患者的RQLQ评分高于治疗前,且实验组明显高于对照组,组间比较差异有统计学意义(t=49.724,P<0.05)。结论 以我院自制的苍夷通窍熏蒸液联合鼻渊通窍颗粒内服疗法治疗AR,不仅能够有效减轻患者的临床症状,提高其日常生活质量,而且具有安全经济、不良反应低等特点,可为该疾病在中医药疗法中提供了一种新的治疗选择和临床依据,并且可为我院带来一定的社会和经济效益。

 Abstract:Objective To investigate the clinical efficacy of Cangyi Tongqiao fumigation solution combined with oral administration of Biyuan Tongqiao granules in the treatment of allergic rhinitis(AR).  Methods A total of 70 patients diagnosed with AR at the Otorhinolaryngology Department of Inner Mongolia Baotou Steel Hospital, between July 2023 and November 2024 were enrolled and sequentially randomly divided into control group and experimental group, with 35 patients in each group. The control group was treated with oral Biyuan Tongqiao granules, while the experimental group was additionally treated with hospital-prepared Cangyi Tongqiao fumigation solution applied for oral and nasal steam therapy. Symptom severity was assessed using a visual analogue scale (VAS) score, and the treatment efficacy, drug safety and quality of life were evaluated using the Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) before and after treatment in two groups.  Results After treatment, both groups showed significant improvements in nasal congestion, itching, sneezing and watery nasal discharge, with the experimental group showing greater symptom relief than the control group, the differences between the two groups were statistically significant(t=16.494, 19.160, 19.832, 15.885; all P<0.05). The total effective rate in the experimental group was 82.86%, which was significantly higher than that of the control group (57.14%), the difference between the two groups was statistically significant(χ2=8.413, P<0.05). The incidence of adverse reactions during treatment was tow and comparable between the two groups (χ2=0.000, P>0.05). After treatment, RQLQ scores were significantly improved in both groups, with the experimental group showing a greater increase than the control group, the difference between the two groups was statistically significant (t=49.724, P<0.05).  Conclusion The combination of hospital-prepared Cangyi Tongqiao fumigation solution and oral Biyuan Tongqiao granules can effectively alleviate clinical symptoms and improve the quality of life in patients with AR. This approach is safe, cost-effective, and associated with minimal adverse effects, providing a new therapeutic option and clinical reference for the management of allergic rhinitis with Traditional Chinese Medicine, while also offering potential social and economic benefits to our hospital.

基金项目:
?基金项目:中国金属学会冶金安全与健康分会健康卫生科研项目(jkws202378)
作者简介:
参考文献:

 参考文献

[ 1 ] 王明杰,陈超林,林莉.孟鲁司特钠联合鼻渊通窍颗粒对变应性鼻炎患儿症状及炎症反应的改善作用[J].现代实用医学,2020,32(11):1386-1387.
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