中国冶金工业医学杂志

替硝唑联合苦参凝胶治疗细菌性阴道病的临床研究

作者：王宇晗

分类号：R 7113

出版年,卷(期):页码：2016,33(4):384-385

摘要：

目的研究替硝唑联合中成药苦参凝胶调节微生态环境对治疗细菌性阴道病(bacterial vaginosis，BV)的临床意义。方法选取2013年11月至2015年5月我院符合BV诊断的女性患者102例，采用随机、剂量组平行对照临床试验，分为替硝唑组(对照组)、联合应用替硝唑及苦参凝胶组（治疗组），在停药的第1周、4周及8周分别随访患者 1 次，采用Amsel 标准进行 BV诊断及疗效评价。结果两组患者入组及第1次随访时各项指标无显著性差异，但是在第2次随访中显示对照组的疗效欠佳，且停药8周后对照组的复发率明显高于治疗组。结论苦参凝胶可以改善阴道微生态环境，治疗BV有效率高于对照组，且复发率低，安全有效。

关键词：细菌性阴道病；替硝唑；苦参凝胶

ObjectiveTo explore the clinical significance of tinidazole combined with Chinese medicine sophora gel for regulating the ecological environment and the treatment of bacterial vaginosis (BV).Methods102 cases of BV were selected from November 2013 to May 2013 in our hospital,by random,dose group parallel controlled clinical trial was used.The cases were divided into tinidazole groups(contrast group) and tinidazole combined with sophora gel group(treatment group).Follow\|up of patients were in 1 week,4 weeks and 8 weeks respectively.The diagnosis and curative effect for BV were evaluated by Amsel standard.ResultsThere was no significant difference between two groups at the time of beginning and the first follow\|up,but showed poor curative effect in the contrast group at the second follow\|up and the rate of recurrence in contrast group was obviously higher than that of treatment group after discontinuation for 8 weeks.ConclusionSophora gel can improve vaginal micro ecological environment and is safe and effective,the rate of efficient for BV is higher,the rate of recurrence is lower.Key Words:Bacterial vaginosis;Tinidazole;Sophora gel

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参考文献：

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