中国冶金工业医学杂志

动态心电图监测美托洛尔与稳心颗粒联合治疗心律失常的疗效观察

分类号：R 5417

出版年,卷(期):页码：2018,35(3):255-256

摘要：

1重庆市九龙坡区人民医院，重庆 401329；2重庆医科大学研究生院摘要：目的利用动态心电图监测美托洛尔与稳心颗粒联合治疗心律失常的临床疗效。方法将82例心律失常患者随机分为对照组与实验组，每组各41例，对照组给予美托洛尔治疗，实验组给予美托洛尔与稳心颗粒联合治疗，比较两组的临床治疗效果，观察治疗前后24 h动态心电图的变化与不良反应发生情况。结果治疗后，实验组总有效率9512%，对照组5854%，组间差异有统计学意义（P＜005）。两组早搏次数较治疗前均有所减少，且实验组减少情况优于对照组（P＜005）。用药治疗期间，实验组不良反应发生率1951%，对照组1463%，组间比较差异无统计学意义（P＞005）。结论美托洛尔与稳心颗粒联合治疗心律失常，可有效改善患者的临床症状，且不良反应发生率较低，可在临床推广。关键词：心律失常；美托洛尔；稳心颗粒；24 h动态心电图

Abstract：ObjectiveTo observe the clinical effect of metoprolol combined with Wenxin granules for arrhythmia by ambulatory electrocardiography（AECG） Methods82 patients with arrhythmia were randomly divided into two groups，each with 41 cases Only metoprolol were taken in the control group，while combined therapy of Wenxin granules and metoprolol were underwent in the treatment group The clinical effect in both groups were compared，24 hour dynamic electrocardiogram and adverse reaction before and after treatment in the two groups were observed and compared ResultsAfter treatment，the total effective rate was 9512% in the treatment group and 5854% in the control group，the difference was statistically significant（P＜005） The premature beat in two groups were improved compared with those before treatment（P＜005），and the improvements in the treatment group were superior to those in the control group（P＜005） During treatment，the incidence rate of adverse reaction was 1951% in the treatment group and 1463% in the control group，the difference was no statistically significant（P＞005） ConclusionThe therapy of metoprolol combined with Wenxin granules for patients with arrhythmia can effectively improve the clinical symptoms，has low incidence rate of adverse effect，and is worthy to be promoted in clinical practiceKey Words:Arrhythmia；Metoprolol；Wenxin granules；24 hour dynamic electrocardiogram

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参考文献：

[1\]陈修，陈维洲，曾贵云，等．心血管药理学［M］．3 版．北京：人民卫生出版社，1989：456

［2］娄菊利．步长稳心颗粒与美托洛尔联用治疗心律失常的疗效及耐受性观察\[J\]．中国医药指南，2015，9（7）：217

［3］陈晓晓，陈维美托洛尔联合稳心颗粒治疗冠心病室性心律失常的疗效观察［J］．实用心脑肺血管病杂志，2013，21（8）：51\|52．

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