Abstract：Objective To explore the diagnostic value of C-reactive protein（CRP）, procalcitonin（PCT） and serum amyloid A（SAA）in pediatric bacterial infections. Methods 78 children with bacterial infections were selected as bacterial group, 78 children with viral infections as virus group, 78 healthy children as control group. PCT, CRP and SAA were tested and the performance in the detection of bacterial infections were compared in three groups. Results CRP and SAA in the bacterial group and the virus group were higher than those in the control group, and the CRP and SAA in the bacterial group were higher than those in the virus group. The difference between the two groups was statistically significant（P＜0.05）. The PCT of the bacterial group was higher than that of the virus group and the control group, the difference was statistically significant（P＜0.05）, and there was no significant difference between the virus group and the control group（P＞0.05）. PCT and CRP combined with SAA had the best diagnostic results. Conclusion Combined detection of PCT, CRP, and SAA is beneficial to identify pediatric bacterial infections, and its sensitivity and specificity are high, which is helpful to improve the clinical diagnosis and reduce the misdiagnosis rate.
Key Words：C-reactive protein; Procalcitonin; Serum amyloid A; Bacterial infectious disease in children; Clinical diagnosis