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电子期刊 >> 正文 |
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摘要：
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罗哌卡因是一种新型酰胺类局麻药,较等效剂量的布比卡因对中枢神经及心血管毒性发生率低[1,2],在高浓度下可产生深度的感觉和运动神经阻滞[3],而在低浓度下具有高度感觉和运动神经分离阻滞作用.本文对低浓度0.4%、0.5%罗哌卡因重比重液用于腰麻-硬膜外联合阻滞的安全性、可行性和有效性及作用特点进行了对照研究,报告如下.
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参考文献：
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Nancarrow C.Rutten AJ.Runciman WB Myocardial and cerebral concentrations and the mechanisms of death after fatal intravenous doses of lidocaine,bupivacaine and ropivacaine in the sheep 1989 Scott D.Lee A.Fagan D Acute toxicity of ropivacaine copared with that of bupivacaine 1989 Mcclure JH Ropivacaine 1996 van Kleef JW.Veering BT.Burm AG Spinal anesthesia with ropivacaine:a double-blind study on the efficacy and safety of 0.5% and 0.75% solutions in patients undergoing minor lower limb surgery 1994 Rosenberg PH.Kytta J.Alila A Absorption of bupivacaine,etidocaine,ligncocaine and ropivacaine into Nhaptane,rat sciatic nerve and human extradural and subcutaneous fat 1986 刘俊杰.赵俊 现代麻醉学 1997
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